mouse monoclonal IgG1; ARID1B Antibody (KMN1) is an IgG1 κ mouse monoclonal ARID1B antibody (also designated ARID1B antibody) that detects the ARID1B protein of mouse, rat and human origin by WB and IP. ARID1B Antibody (KMN1) is available as both the non-conjugated anti-ARID1B antibody form, as well as multiple conjugated forms of anti-ARID1B antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. BAF250b (BRG1-associated factor 250b), also known as ARID1B (AT-rich interactive domain-containing protein 1B) or hOsa2 (Osa homolog 2), is a 2,236 amino acid protein that contains 1 ARID domain. BAF250b has a BC box motif, associates with elongin C in a BC box-dependent manner, and, together with cullin 2 and Roc1, assembles into an E3 ubiquitin ligase that participates in ubiquitination of histone H2B. Smad2 and Smad3 interact with BRG1, BAF250b, BAF170 and BAF155, which are core components of the SWI/SNF chromatin-remodeling complex. Localizing to nucleus, BAF250b is widely expressed with high levels in heart, skeletal muscle and kidney. The BAF250b gene is conserved in chimpanzee, dog, mouse, rat, chicken, zebrafish, mosquito and C.elegans, and maps to human chromosome 6q25.3. BAF250b exists as three alternatively spiced isoforms.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.