DESCRIPTION

• Mw: 24.8 kDa
• Tag: Myc-DDK
• Accn: NM_001161013
• Type: Human Tagged ORF Clone Lentiviral Particle
• Refseq: NM_001161013.2, NP_001154485.1
• Status: 7 Weeks*
• Symbol: ARMC10
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Category: cDNA Clones
• Locus Id: 83787
• Orf Size: 675 bp
• Synonyms: PNAS-112; PNAS112; PSEC0198; SVH
• Refseq Orf: 678 bp
• Uniprot Id: Q8N2F6
• Refseq Size: 2297 bp
• Availability: 7 Weeks
• Cytogenetics: 7q22.1
• Gene Summary: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
• Sequence Data: ORF Nucleotide Sequence ( show hide ) The ORF insert of this clone is exactly the same as(RC228156).
• Oti Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Oti Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Protein Families: Transmembrane
• Mammalian Cell Selection: Puromycin