BRDG 1 Antibody (N-term F31) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 26228
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: STAP1
Other Names: Signal-transducing adaptor protein 1, STAP-1, BCR downstream-signaling protein 1, Docking protein BRDG1, Stem cell adaptor protein 1, STAP1, BRDG1
Availability: 2 weeks
Bio Background: STAP1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.
Bio References: Ma,J., Atherosclerosis 191 (1), 63-72 (2007)Beausoleil,S.A., Nat. Biotechnol. 24 (10), 1285-1292 (2006)Gstaiger,M., Science 302 (5648), 1208-1212 (2003)Minoguchi,M., J. Biol. Chem. 278 (13), 11182-11189 (2003)
Primary Accession: Q9ULZ2
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP1475b was selected from the N-term region of human STAP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.