MAE-H5143-100ug MAE-H5143-1mg
Human Matriptase / ST14 Catalytic Domain Protein, His Tag (active enzyme)
ACROBiosystems
DESCRIPTION
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing; Cleaves various synthetic substrates with Arg or Lys at the P1 position and prefers small side-chain amino acids, such as Ala and Gly, at the P2 position.
DETAILS
- Tag: N-10×His
- Host: E. coli
- Size: 1mg
- Buffer: 50 mM Tris, 150 mM NaCl, pH 7.5
- Format: Liquid
- Purity: 90%
- Source: Human Matriptase / ST14 Catalytic Domain Protein, His Tag (MAE-H5143) is expressed from E. coli cells. It contains AA Gly 596 - Val 855 (Accession # NP_068813).
- Storage: -70℃
- Category: Enzymes
- Molecule: Matriptase
- Conjugate: Unconjugated
- Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
- Exp Region: Gly 596 - Val 855
- Swiss-prot: NP_068813
- Package Size: 1mg*1
- Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 30.6 kDa. The protein migrates as 27-28 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 30.6 kDa
- Shipping Condition: Dry ice
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html