DESCRIPTION

• Shiptemp: -80°C (dry ice)
• Synonyms: cyclin-dependent kinase 2, CDKN2, cyclin dependent kinase 2
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/Assay Kit
• References: Uzma A. et al., Nature Review Drug Discovery 14:130-146 (2015)
• Description: Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle. CDKs are active only when bound to their regulator proteins, cyclins. CDK activity is tightly controlled for successful cell division. Since abnormal cell division represents cancer pathology, controlling CDK activity has been shown as a promising therapeutic strategy. In particular, CDK2 plays an important role in DNA replication. The CDK2 Assay Kit is designed to measure CDK2/CyclinA2 activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent.
• Methodology: Chemiluminescent
• Supplied As: The CDK2 Assay Kit comes in a convenient 96-well format, with enough purified recombinant CDK2/CyclinA2 enzyme, CDK substrate peptide, ATP and kinase assay buffer for 100 enzyme reactions.
• Unspsc Code: 41121811
• Unspsc Name: Laboratory microchemistry kits
• Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 79597, 79600, 78487
• Storage Stability: Stable at least 6 months from date of receipt. when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
• Scientific Category: Kinase
• Instructions for Use: See assay kit datasheet for detailed protocol.