mouse monoclonal IgG1; Orai2 Antibody (G-5) is an IgG1 κ mouse monoclonal Orai2 antibody (also designated ORAI2 antibody, C7orf19 antibody, CPCIP2 antibody, or TMEM142B antibody) that detects the Orai2 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Orai2 Antibody (G-5) is available as both the non-conjugated anti-Orai2 antibody form, as well as multiple conjugated forms of anti-Orai2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Orai2 (orai calcium release-activated calcium modulator 2), also known as CBCIP2 (CAP-binding protein complex-interacting protein 2) or TMEM142B (transmembrane protein 142B), is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins. Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response. Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.