3CL Protease (B.1.1.529, Omicron Variant), (SARS-CoV-2) Recombinant

DESCRIPTION

Purified recombinant SARS-CoV-2 protease 3CL (3C-like protease, also known as MPro) full length encompassing amino acids 1-306 (end). This construct does not contain a tag. The protein corresponds to SARS-CoV-2 variant B.1.1.529 (Omicron Variant), originally discovered in South Africa, and contains mutation P132H.

DETAILS

Aa: 1-306(end)
Mw: 34 kDa
Format: Aqueous buffer solution
Purity: ≥90%
Genbank: YP_009725301
Species: SARS-CoV-2
Mutation: P132H
Shiptemp: -80°C (dry ice)
Synonyms: 3C-like protease, SARS protease, SARS-ncov protease, nsp5, 101328-1, 101328-2, Omicron
Warnings: Avoid freeze/thaw cycles.
Category: Coronavirus/Protein
Constructs: 3CL Protease (B.1.1.529, Omicron Variant) (1-306(end))(P132H)(SARS-CoV-2)
Description: Purified recombinant SARS-CoV-2 protease 3CL (3C-like protease, also known as MPro) full length encompassing amino acids 1-306 (end). This construct does not contain a tag. The protein corresponds to SARS-CoV-2 variant B.1.1.529 (Omicron Variant), originally discovered in South Africa, and contains mutation P132H.
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% Glycerol, and 3 mM DTT.
Unspsc Code: 12352202
Unspsc Name: Proteins
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Product Type: Protein
Biosafety Level: Not applicable (BSL-1)
Assay Conditions: Assay was done according to the 3CL Protease, MBP-tagged (SARS-CoV-2) Assay Kit (BPS Bioscience #79955-1) with 3CL Protease (B.1.1.529, Omicron Variant) titrated from 90 ng/rxn to 0 ng/rxn.
Storage Stability: At least 6 months at -80°C.
Scientific Category: Coronavirus