DESCRIPTION

• Category: REAGENTS
• Keywords: T10, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, OKT10, flow cytometry antibody, flow cytometry antibodies, facs antibody, primary antibody, monoclonal antibody, anti-human antibody, Anti human, anti human antibody anti-CD38, CD38, anti CD38, OKT10, Clone OKT10, conjugated antibody, conjugated flow cytometry antibody, CD38 antibody, CD Marker, CD Markers, CD Antigen, PE CD38, PE, PE Antibody
• Paragraph 1: CD38 is a type II transmembrane glycoprotein of 45 kDa with a protein core of 35 kDa. The CD38 antigen is expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. It is also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. The antigen is expressed during the early stages of T- and B-lymphocyte differentiation, is lost during the intermediate stages of maturation, and then reappears during the final stages of maturation. The CD38 antigen is expressed on 90% of CD34+ cells, and is not expressed on pluripotent stem cells. Coexpression of CD38 antigen on CD34+ cells indicates lineage commitment of those cells. CD38 is a counter-receptor of CD31. It is also expressed in T- and B-acute lymphoblastic leukemia (ALL), Burkitts lymphoma, multiple myeloma, acute myeloid leukemia (AML), and chronic lymphocytic leukemia (CLL). The OKT10 directed against human CD38 antigen.
• Paragraph 2: Each lot of these antibodies has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg (unconjugated, Biotin) or 5µl (conjugated) of these products are sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance. Non-human primate cross-reactivity has been validated using Caprico’s purified and PE, APC, and Biotin conjugated clone OKT10 products. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.
• Bullet Point 1: Clone OKT10, a mouse monoclonal antibody, recognizes a 45 kDa, type II transmembrane cell surface glycoprotein known as CD44
• Bullet Point 2: Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
• Bullet Point 3: >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
• Bullet Point 4: More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.
• Manufacturer Sku: 100824