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9000337

(R)-Acenocoumarol

Cayman Chemical

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DETAILS

  • Inchi: InChI=1S/C19H15NO6/c1-11(21)10-15(12-6-8-13(9-7-12)20(24)25)17-18(22)14-4-2-3-5-16(14)26-19(17)23/h2-9,15,22H,10H2,1H3/t15-/m1/s1
  • Purity: ≥98%
  • Raptas: Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis
  • Smiles: O=C1C([C@@](CC(C)=O)([H])C2=CC=C([N+]([O-])=O)C=C2)=C(O)C3=CC=CC=C3O1
  • Inchikey: VABCILAOYCMVPS-OAHLLOKOSA-N
  • Cas Number: 66556-77-2
  • Formulation: A crystalline solid
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C19H15NO6
  • Formula Weight: 353.3
  • Shelf Life Days: 730

DESCRIPTION

An enantiomer of the short-lived oral anti-coagulant acenocoumarol with a longer plasma elimination half-life (6.6 hours) and slower plasma clearance (1.9 L/hour), compared to the (S)-enantiomer (1.8 hours, 28.5 L/hour); rapidly absorbed from the gastrointestinal tract with essentially complete oral bioavailability; more potent in vivo than the (S)-enantiomer