DESCRIPTION

• Form: Total IgY fraction
• Gene: VIM
• Host: Chicken
• Rrid: AB_2492283
• Type: Primary Antibody
• Buffer: PBS + 10 mM NaN3.
• Target: Vimentin
• Isotype: IgY
• Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
• Shipping: Blue Ice
• Synonyms: CTRCT30 antibody, Epididymis luminal protein 113 antibody, FLJ36605 antibody, HEL113 antibody, VIM antibody, VIME_HUMAN antibody, Vimentin antibody
• Clonality: Polyclonal
• Immunogen: Recombinant human vimentin purified from E. coli.
• Expiration: After date of receipt, stable for at least 1 year at -20°C.
• Specificity: Specific for the ~50 kDa Vimentin protein.
• Applications: WB, IHC, ICC
• Ncbi Gene Id: 7431
• Conjugate Exem: Unconjugated
• Physical State: Liquid
• Quality Control: Western blots performed on each lot.
• Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
• Molecular Weight: 50
• Production Notes: Total IgY fraction.
• Dilution Range Wb: 1:1000
• Immunogen Species: Human
• Dilution Range Icc: 1:500-1:10,000
• Dilution Range Ihc: 1:500-1:5000
• Species Reactivity: Human, Mouse, and Rat
• Target Description: Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).
• Expected Reactivity: Bovine, Canine, Feline, Goat, Guinea Pig, Hamster, Horse, Non-Human Primate, Rabbit, Sheep, Vole
• Uniprot Number Immunogen Species: P08670

PROMOTION TERMS