Nec-3a

DESCRIPTION

Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM. This compound successfully impedes the autophosphorylation activity within the RIP1 kinase domain.

DETAILS

Cas: 1504558-72-8
Purity: 98%
Smiles: C(CO)(=O)N1[C@@H]([C@]2(C(=N1)C=3C(CC2)=CC=C(OC)C3)[H])C4=CC(F)=C(OC(F)(F)F)C=C4
Category: Compound
Molecular Weight: 438.37
Molecular Formula: C21H18F4N2O4

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