DESCRIPTION

• Aa: 2-629(end)
• Mw: 95 kDa
• Tags: N-terminal GST-tag
• Genbank: NM_004714
• Species: Human
• Uniprot: Q9Y463
• Shiptemp: -80°C (dry ice)
• Synonyms: Minibrain-Related Kinase, MRK
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/tyrosine
• References: 1. Mao, J. et al., JBC. 277(38): 35156-35161, 2002.2. Guimera, J. W. et al., Genomics. 57(3): 407-418, 1999.
• Description: Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1B (DYRK1B), also known as Minibrain-Related Kinase (MIRK), GenBank Accession No. NM_004714, a.a. 2-629(end), with N-terminal GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW= 95 kDa.
• Formulation: 40 mM Tris-HCl, pH 8.0. 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% Glycerol and 3 mM DTT.
• Supplied As: Aqueous buffer solution.
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Assay Conditions: Assay was done in Kinase buffer containing DYRKtide substrate peptide 1 (0.2 mg/ml) and20 µM ATP. Reaction was done at 30°C for 35 min. Amount of ATP transferred was calculated using Kinase-Glo reagent (Promega).
• Related Products: 40110, 40007, 40053, 79700, 78487
• Specific Activity: ≥500 pmole/min/µg
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Kinase