ZM-447439

DESCRIPTION

ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.

DETAILS

Cas: 331771-20-1
Purity: 99.11%
Smiles: COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCOCC1
Category: Compound
Molecular Weight: 513.59
Molecular Formula: C29H31N5O4

Lead Time: < 1 week