DESCRIPTION

• Target: ATG4B
• Gene Id: 23192
• Conjugate: Biotin
• Immunogen: Synthetic peptide from the N-terminal to mid of Human ATG4B (aa. 94-106)
• References: 1. Kabeya Y., et al. (2004) J Cell Sci. 117: 2805-2812. 2. Tanida I., et al. (2004) J Biol Chem. 279: 36268-36276. 3. Hemelaar J., et al. (2003) J Biol Chem. 278: 51841-51850.
• Swiss-prot: Q9Y4P1
• Specificity: Detects ~44 kDa.
• Applications: WB | ICC/IF
• Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• Host Species: Rabbit
• Product Type: Polyclonal
• Purification: Peptide Affinity Purified
• Concentration: 1 mg/ml
• Research Areas: Cancer | Autophagy | Cardiovascular System | Heart | Cell Signaling
• Storage Buffer: PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Accession Number: NP_037457.3
• Alternative Names: MGC1353 Antibody, Autophagy-related cysteine endopeptidase 1 Antibody, ATG4B Antibody, hAPG4B Antibody, AUT-like 1 cysteine endopeptidase Antibody, Cysteine protease ATG4B Antibody, Autophagy-related protein 4 homolog B Antibody, Autophagin-1 Antibody, EC:3.4.22.- Antibody, ATG4B_HUMAN Antibody, APG4B Antibody, APG4 autophagy 4 homolog B Antibody, AUTL1 Antibody, KIAA0943 Antibody, Autophagy related cysteine endopeptidase 1 Antibody, Autophagin 1 Antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) Antibody, AUT like 1 cysteine endopeptidase Antibody, Autophagy related protein 4 homolog B Antibody
• Antibody Dilution: WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
• Cite This Product: StressMarq Biosciences Cat# SPC-630D-BI, RRID: AB_2705116
• Immunogen Species: Human
• Tissue Specificity: Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
• Storage Temperature: Conjugated antibodies should be stored according to the product label
• Shipping Temperature: Blue Ice or 4ºC
• Cellular Localization: Cytoplasm
• Scientific Background: Autophagy related 4B, cysteine peptidase (ATG4B or APG4B) is a C-54 cysteine protease that also belongs to the family of autophagin poteins. Specifically it cleaves LC3, and mutations can be associated with strong inhibition of autophagosome formation.
• Certificate of Analysis: A 1:1000 dilution of SPC-630 was sufficient for detection of ATG4B in 15 µg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
• Species Reactivity Full Name: Human | Mouse