DESCRIPTION

• Aa: 21-220
• Mw: 48.7 kDa
• Tags: C-terminal Fc fusion (Human IgG1)
• Notes: The aggregation state of this product has been confirmed to be <10%.
• Format: Aqueous buffer solution
• Genbank: NM_000610
• Species: Human
• Uniprot: P16070
• Shiptemp: -80°C (dry ice)
• Synonyms: epican, extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, phagocytic glyco-protein I (PGP-1), homing cell adhesion molecule (HCAM)
• Warnings: Avoid freeze/thaw cycles. Protein may be diluted to _x0001_≥ 100 µg/ml in PBS + glycerol and stored at -80°C.
• Category: Immunotherapy/Protein
• References: 1. Prince, M.E., et al., Proc. Natl. Acad. Sci. (USA). 2006; 104(3): 973-978. 2. Lei, D., et al., Clin. Canc. Res. 2008; 14: 6751-6760.
• Description: Human CD44, also known as epican, extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, or phagocytic glyco-protein I (PGP-1), GenBank Accession No. NM_000610, a.a. 21-220, fused with Fc region of human IgG, expressed in a HEK293 cell expression system. MW = 48.7 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for studying protein binding and for screening small molecules and antibodies.
• Host Species: human
• Product Type: Protein
• Host Cell Line: HEK293
• Biosafety Level: Not applicable (BSL-1)
• Endotoxin Level: <1 EU/µg
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Immunotherapy
• Instructions for Use: Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.