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1549658-5mg 1549658-500ug

Stauprimide

Biogems

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DESCRIPTION

Stauprimide is a staurosporine that interacts with the NME2 (PUF) transcription factor to down-regulate c-Myc expression. This biological effect primes cells for further cellular differentiation.

DETAILS

  • Purity: ≥98%
  • Synonyms: N-Benzoyl-7-oxostaurosporine, AKOS024457783
  • Cas Number: 154589-96-5
  • References: Zaret, K. S. (2009). Using small molecules to great effect in stem cell differentiation. Cell stem cell, 4(5), 373-374. Zhu, S., Wurdak, H., & Schultz, P. G. (2010). Directed embryonic stem cell differentiation with small molecules. Future medicinal chemistry, 2(6), 965-973. Li, W., & Ding, S. (2010). Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming. Trends in pharmacological sciences,31(1), 36-45.
  • Application: FA
  • Formulation: Crystalline solid
  • Chemical Name: N-[(2S,3R,4R,6R)-3-Methoxy-2-methyl-16,18-dioxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide
  • Molecular Weight: 584.6
  • Molecular Formula: C35H28N4O5
  • Storage Conditions: Product should be kept at -20°C.
  • Pubchem Openeye Can Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(=O)NC6=O)N(C)C(=O)C9=CC=CC=C9)OC