Anti-MEK2 Antibody [SD207-08]

DESCRIPTION

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: P36507 Human;SwissProt: Q63932 Mouse
Clone Id: SD207-08
Clonality: Recombinant Rabbit monoclonal Antibody
Conjugate: Non-conjugated
Alias Names: Cardiofaciocutaneous syndrome antibody CFC syndrome antibody CFC4 antibody Dual specificity mitogen activated protein kinase kinase 2 antibody Dual specificity mitogen-activated protein kinase kinase 2 antibody ERK activator kinase 2 antibody FLJ26075 antibody MAP kinase kinase 2 antibody map2k2 antibody MAPK / ERK kinase 2 antibody MAPK/ERK kinase 2 antibody MAPKK 2 antibody MAPKK2 antibody MEK 2 antibody MEK2 antibody Microtubule associated protein kinase kinase 2 antibody Mitogen activated protein kinase kinase 2 antibody Mitogen activated protein kinase kinase 2 p45 antibody MKK 2 antibody MKK2 antibody MP2K2_HUMAN antibody OTTHUMP00000165826 antibody OTTHUMP00000165827 antibody PRKMK 2 antibody PRKMK2 antibody
Application: WB,IF-Cell,IF-Tissue,IHC-P,IP,FC
Epitope Region: Synthetic peptide within human MEK2 aa 1-50/400.
Protein Target: MAP kinase kinase 2, MAPKK 2, MEK 2, MAP2K2
Target Species: Human,Mouse
Species Reactivity: Human,Mouse