IT1-H52W3-100ug IT1-H52W3-1mg
Human Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free
ACROBiosystems
DESCRIPTION
Integrin alpha 11 beta 1 is a receptor for collagen. The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids. The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.
DETAILS
- Tag: C-10×His | Native
- Host: HEK293
- Size: 100ug
- Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
- Format: Powder
- Purity: 90%
- Source: Human ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21-Asp 728 (ITGB1) (Accession # Q9UKX5-1 (L524R) (ITGA11) & P05556-1 (ITGB1)).
- Storage: -20℃
- Category: Bio-Markers & CD Antigens
- Molecule: Integrin alpha 11 beta 1
- Accession: NP_001004439.1 (L524R) (ITGA11) & NP_002202.2 (ITGB1)
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Phe 23 - Pro 1141 (ITGA11) & Gln 21-Asp 728 (ITGB1)
- Swiss-prot: Q9UKX5-1 (L524R) (ITGA11) & P05556-1 (ITGB1)
- Package Size: 100ug*1
- Characteristics: Human ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA11 and ITGB1, has a calculated MW of 131.6 kDa (ITGA11) and 82.7 kDa (ITGB1). Subunit ITGA11 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 150-165 kDa (ITGA11) and 90-120 kDa (ITGB1) respectively due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 131.6 kDa (ITGA11) & 82.7 kDa (ITGB1)
- Shipping Condition: RT
- Species Reactivity: Human
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