40871
JNK1-β1(K55M), Kinase Deficient, GST-tag Recombinant
BPS Bioscience
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DESCRIPTION
Human JNK1-β1(K55M), also known as MAPK8 (K55M) (GenBank Accession No. NM_139046), full length with mutation of lysine55 to methionine, and N-terminal GST-tag, MW=~70 kDa, expressed in E. coli. The K55M mutation prevents ATP binding, making the kinase inactive.
DETAILS
- Aa: full length
- Mw: ~70 kDa
- Tags: N-terminal GST-tag
- Format: Aqueous buffer solution
- Genbank: NM_139046
- Species: Human
- Uniprot: P45983
- Mutation: K55M
- Shiptemp: -80°C (dry ice)
- Synonyms: JNK1b, mitogen-activated protein kinase 8, MAPK8b, Stress-Activated Protein Kinase, SAPK
- Warnings: Avoid freeze/thaw cycles.
- Category: Kinase/Kinase Substrates
- References: 1. Derijard, B. et al., Cell. 76(6):1025-37 (1994). 2. Kolodziejczyk, S M. et al., Curr. Biol. 11(16):1278-82 (2001).
- Description: Human JNK1-β1(K55M), also known as MAPK8 (K55M) (GenBank Accession No. NM_139046), full length with mutation of lysine55 to methionine, and N-terminal GST-tag, MW=~70 kDa, expressed in E. coli. The K55M mutation prevents ATP binding, making the kinase inactive.
- Formulation: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 10% glycerol, and 3 mM DTT.
- Unspsc Code: 12352202
- Unspsc Name: Proteins
- Applications: Useful as a substrate for kinase assays.
- Product Type: Protein
- Biosafety Level: Not applicable (BSL-1)
- Specific Activity: inactive
- Storage Stability: At least 6 months at -80°C.
- Scientific Category: Kinase/Serine-Threonine