30-1588
Anti-CD42b Monoclonal Antibody (Clone:AK2)-Low Endotoxin
Abeomics
DESCRIPTION
CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
DETAILS
- Gene: GP1BA
- App Id: FACS, IP, WB, ICC, ELISA
- Antigen: CD42b
- Gene Id: 2811
- Isotype: Mouse IgG1
- Format Id: Low Endotoxin
- Clone Name: AK2
- Uniprot Id: P07359
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Purification: Purified by protein-A affinity chromatography
- Reactivity Id: Human
- Alternative Name: GP1BA
- Storage Condition: Store at 2-8°C. Do not freeze.
- Immunogen Information: Human platelets
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