GCN5 (GCN5L2) Antibody (N-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 2648
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: KAT2A
Other Names: Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5
Availability: 2 weeks
Bio Background: GCN5L2 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. This protein has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles.
Bio References: Kikuchi, H., et al., Gene 347(1):83-97 (2005).Gangisetty, O., et al., Oncogene 23(14):2559-2563 (2004).Lusic, M., et al., EMBO J. 22(24):6550-6561 (2003).Fulco, M., et al., Mol. Cell 12(1):51-62 (2003).Liu, X., et al., J. Biol. Chem. 278(22):20405-20412 (2003).
Other Accession: Q8N1A2
Primary Accession: Q92830
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP1078a was selected from the N-term region of human GCN5L2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.