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sc-398595 SAMPLE sc-398595

Promo Available Scientist.com Supplier

Fos B (F-7)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG1; Fos B Antibody (F-7) is an IgG1 κ mouse monoclonal Fos B antibody that detects the Fos B protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Fos B Antibody (F-7) is available as both the non-conjugated anti-Fos B antibody form, as well as multiple conjugated forms of anti-Fos B antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPAresponse elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: P53539
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, IHC(P), ELISA
  • Human Gene Id: 2354
  • Mouse Gene Id: 14282
  • Protein Target: Fos B
  • Human Gene Name: FOSB
  • Mouse Gene Name: Fosb
  • Species Reactivity: mouse, rat, human

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.