35-1310-50 35-1310
Polyclonal Antibody to eIF4B (phospho-Ser422)
Abeomics
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DESCRIPTION
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
DETAILS
- Gene: EIF4B
- App Id: WB,IHC
- Antigen: eIF4B (phospho-Ser422)
- Gene Id: 1975
- Isotype: Rabbit IgG
- Format Id: Purified
- Uniprot Id: P23588
- Host Animal: Rabbit
- Clonality Id: Polyclonal
- Reactivity Id: Human,Mouse,Rat
- Product Content: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Application Note: Predicted MW: 80kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
- Storage Condition: Store the antibody at 4°C, stable for 6 months. For ong-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
- Immunogen Information: Peptide sequence around phosphorylation site of Serine 422 (T-G-S(p)-E-S) derived from Human eIF4B.