Anti-NUDT5 Antibody [JE56-41]

DESCRIPTION

This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: Q9UKK9 Human
Clone Id: JE56-41
Clonality: Recombinant Rabbit monoclonal Antibody
Conjugate: Non-conjugated
Alias Names: ADP sugar pyrophosphatase antibody ADP-sugar pyrophosphatase antibody hYSAH 1 antibody hYSAH1 antibody Nucleoside diphosphate linked moiety X motif 5 antibody Nucleoside diphosphate linked moiety X type motif 5 antibody Nucleoside diphosphate-linked moiety X motif 5 antibody Nudix (nucleoside diphosphate linked moiety X) type motif 5 antibody Nudix motif 5 antibody Nudix type motif 5 antibody NUDT 5 antibody Nudt5 antibody NUDT5_HUMAN antibody YSA1 antibody YSA1H antibody
Application: WB,IHC-P
Epitope Region: Recombinant protein within human NUDT5 aa 1-150.
Protein Target: NUDT5
Target Species: Human
Species Reactivity: Human