E4735Hu
Human Fad-linked Sulfhydryloxidase Alr, GFER ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
[Isoform 1]: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. [Isoform 2]: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
DETAILS
- GeneID: 2671
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 23,449
- Synonyms: Augmenter of liver regeneration;FAD-linked sulfhydryl oxidase ALR;GFER;Hepatopoietin;hERV1
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: GFER
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 5.54ng/L
- Target Protein: GFER
- Detection Range: 10-2000ng/L
- Full Product Name: Fad-Linked Sulfhydryl Oxidase ALR
- Standard Solution: 2400ng/L
- UniProt Accession: P55789