DESCRIPTION

• Aa: 36-162
• Mw: 40.3 kDa
• Tags: C-terminal Fc fusion (Human IgG1)
• Notes: The aggregation state of this product has been confirmed to be <10%.
• Format: Aqueous buffer solution
• Genbank: NM_005214
• Species: Human
• Uniprot: P16410
• Shiptemp: -80°C (dry ice)
• Synonyms: Cytotoxic T-lymphocyte-associated protein 4 CD152
• Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
• Category: Immunotherapy/Protein
• References: 1. Dilek, N., et al., PLOS ONE. 2013 Dec. 23: DOI: 10.1317. 2. Leach, D.R., et al., Science. 1996; 271(5256):1734-1736.
• Description: Human secreted CTLA4 , Fc fusion protein, also known as Cytotoxic T-lymphocyte-associated protein 4 and CD152. GenBank Accession No. NM_005214, a.a. 36-162 expressed in a HEK293 cell expression system. MW = 40.3 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
• Formulation: 40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for studying protein binding and screening small molecular inhibitors
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Endotoxin Level: <1 EU/µg
• Related Products: 71125, 71150, 72009, 71212, 71114
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Immunotherapy