L-erythro Sphinganine (d18:0)

DESCRIPTION

A bioactive sphingolipid; synthetic stereoisomer of sphinganine (d18:0) and D-threo sphinganine (d18:0); induces autophagy in HCT116 cells (12 μM); induces cell cycle arrest of 7R4-LCB1 yeast cells; metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver

DETAILS

Inchi: InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m1/s1
Purity: ≥98%
Raptas: Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cancer|Autophagy||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy||Research Area|Lipid Biochemistry|Sphingolipids
Smiles: OC[C@@H](N)[C@@H](O)CCCCCCCCCCCCCCC
Inchikey: OTKJDMGTUTTYMP-MSOLQXFVSA-N
Cas Number: 6036-76-6
Formulation: A solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C18H39NO2
Formula Weight: 301.5
Shelf Life Days: 1460