JAK3-IN-1

DETAILS

Cas: 1805787-93-2
Purity: 98%
Smiles: O(C)C=1C=C(C=CC1NC=2N=C(NCC3=CC(NC(C=C)=O)=CC=C3)C(Cl)=CN2)N4CCN(C)CC4
Category: Compound
Molecular Weight: 508.02
Molecular Formula: C26H30ClN7O2

DESCRIPTION

JAK3-IN-1 is a selective and orally active JAK3 inhibitor (IC50: 4.8 nM). JAK3-IN-1 displays over 180-fold more selective for JAK3 than JAK1 (IC50: 896 nM) and JAK2 (IC50: 1050 nM).

Lead Time: 4 - 5 weeks