TNNT2 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 7139
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: TNNT2
Other Names: Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2
Availability: 2 weeks
Bio Background: The protein encoded by this gene is thetropomyosin-binding subunit of the troponin complex, which islocated on the thin filament of striated muscles and regulatesmuscle contraction in response to alterations in intracellularcalcium ion concentration. Mutations in this gene have beenassociated with familial hypertrophic cardiomyopathy as well aswith dilated cardiomyopathy. Transcripts for this gene undergoalternative splicing that results in many tissue-specific isoforms,however, the full-length nature of some of these variants has notyet been determined.
Bio References: Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Millat, G., et al. Eur J Med Genet 53(5):261-267(2010)Watt, K.D., et al. Liver Transpl. 16(8):990-998(2010)Koide, K., et al. Heart Vessels 25(3):217-222(2010)
Primary Accession: P45379