Terphenyllin

DESCRIPTION

A flavonoid metabolite with antibacterial properties; active against MRSA-1, MRSA-2, and V. vulnificus (MICs = 31.27-31.47 µg/ml); cytotoxic to HeLa, A549, and HepG2 cells (IC50s = 18.87, 12.33, and 21.2 µM, respectively); inhibits HIV-1 integrase in coupled and strand transfer assays (IC50s = 17.7 and 47.7 µM, respectively)

DETAILS

Inchi: InChI=1S/C20H18O5/c1-24-17-11-16(12-3-7-14(21)8-4-12)20(25-2)19(23)18(17)13-5-9-15(22)10-6-13/h3-11,21-23H,1-2H3
Purity: ≥85%
Raptas: Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antivirals|Integrase Inhibitors||Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS
Smiles: OC1=CC=C(C2=C(OC)C(O)=C(C3=CC=C(O)C=C3)C(OC)=C2)C=C1
Inchikey: YNEMPXKRLPZFAX-UHFFFAOYSA-N
Cas Number: 52452-60-5
Formulation: A solid
Item Origin: Fungus/Aspergillus candidus
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C20H18O5
Formula Weight: 338.4
Shelf Life Days: 1460