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T10854

CNX-500

TargetMol

- Open Babel Depiction O O N H O O O CH 3 N N H HN S N H N NH NH O NH O O H 2 C N H O

DESCRIPTION

CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin. CNX-500 has inhibitory activity against Btk (IC50: 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase EGFR and upstream Src-family kinases.

DETAILS

  • Cas: 1202758-21-1
  • Purity: 98%
  • Smiles: C(CCCC(NCCCOCCOCCOCCCNC(CCCC(NCCCOC1=CC(NC=2N=C(NC3=CC(NC(C=C)=O)=CC=C3)C(C)=CN2)=CC=C1)=O)=O)=O)[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H]
  • Category: Compound
  • Molecular Weight: 961.18
  • Molecular Formula: C48H68N10O9S

Lead Time: 4 - 5 weeks

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