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T10854

CNX-500

TargetMol

- Open Babel Depiction O O N H O O O CH 3 N N H HN S N H N NH NH O NH O O H 2 C N H O

DESCRIPTION

CNX-500, a probe comprising a covalent Btk inhibitor chemically linked to biotin, exhibits significant inhibitory activity against Btk (IC50: 0.5 nM) and can form a covalent bond with Btk. Additionally, CNX-500 has low inhibitory effects on kinase EGFR and upstream Src-family kinases.

DETAILS

  • Cas: 1202758-21-1
  • Purity: 98%
  • Smiles: [H][C@]12CS[C@@H](CCCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCC(=O)NCCCOc3cccc(Nc4ncc(C)c(Nc5cccc(NC(=O)C=C)c5)n4)c3)[C@@]1([H])NC(=O)N2
  • Category: Compound
  • Molecular Weight: 961.18
  • Molecular Formula: C48H68N10O9S

Lead Time: Please Inquire

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