ONO-8130

DESCRIPTION

A selective, orally bioavailable antagonist of the EP1 receptor (Ki = 1.9 nM); suppresses pain associated with cyclophosphamide-induced cystitis in mice

DETAILS

Inchi: InChI=1S/C25H28N2O5S2/c1-16(2)13-27(34(30,31)25-26-17(3)15-33-25)22-11-20-5-4-6-21(20)12-23(22)32-14-18-7-9-19(10-8-18)24(28)29/h7-12,15-16H,4-6,13-14H2,1-3H3,(H,28,29)
Purity: ≥98%
Raptas: Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Pain Research
Smiles: OC(C1=CC=C(COC2=CC(CCC3)=C3C=C2N(S(C4=NC(C)=CS4)(=O)=O)CC(C)C)C=C1)=O
Inchikey: IOXMDBQCUCDLAF-UHFFFAOYSA-N
Cas Number: 459841-96-4
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C25H28N2O5S2
Formula Weight: 500.6
Shelf Life Days: 1460