GCGR Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 2642
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: GCGR
Other Names: Glucagon receptor, GL-R, GCGR
Availability: 2 weeks
Bio Background: This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Primary Accession: P47871
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP8908c was selected from the Center region of human GCGR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.