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T18538

Scientist.com Supplier

MAC glucuronide phenol-linked SN-38

TargetMol

- Open Babel Depiction O O O N H 3 C N O NH HO N CH 3 OH O O O O O CH 3 S N O N OH OH OH O O CH 3 O O O
DESCRIPTION:
MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1].

DETAILS

  • Cas: 2246380-69-6
  • Purity: 98%
  • Smiles: CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OCN(CCS(C)(=O)=O)C(=O)OCc3ccc(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)c(NC(=O)CN(C)C(=O)CCN4C(=O)C=CC4=O)c3)cc12
  • Category: Compound
  • Molecular Weight: 1091.06
  • Molecular Formula: C50H54N6O20S

Lead Time: Please Inquire

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