DESCRIPTION

• Mw: 578.7 Da
• Notes: Can also be used as a substrate for human tissue kallikrein, and the falcipains I - III, the hemoglobin-degrading cysteine proteases from the malaria parasite Plasmodium falciparum .
• Format: DMSO solution
• Formula: C30H38N6O6
• Shiptemp: -20°C or -80°C
• Synonyms: Z-Leu-Arg-AMC, Z-LR-AMC, Benzyloxycarbonyl- L-leucyl- L-arginine 4-methylcoumaryl-7-amide
• Warnings: Protect from direct exposure to light. Avoid freeze/thaw cycles.
• Category: Protease/Substrates
• References: 1. Fonovic, M. et al., Biol Chem 385(6), 505-509 (2004).2. D. Broemme, et al. J. Biol. Chem., 271, 2126 (1996).
• Description: The fluorogenic Cathepsin V substrate is a Z-Leu-Arg-AMC dipeptide. It can be used as a substrate for activity assays of Cathepsins K, L, S, and V. λex 353-380 nm, λem=440-460 nm
• Supplied As: 0.5 mM solution in DMSO (100 µl)
• Unspsc Code: 41105331
• Unspsc Name: Protein chemifluorescent detection reagents or kits or substrates
• Applications: Useful for the study of cathepsin activity, and for screening small molecule inhibitors of cathepsins K, L, S, and V for drug discovery and HTS applications.
• Cas Registry: 156192-32-4
• Product Type: Substrate
• Biosafety Level: Not applicable (BSL-1)
• Storage Stability: Stable at least 6 months from date of receipt, when stored as directed
• Scientific Category: Protease