RS3121 RS3201 MS3231 MS3221 +171
Anti-PRG3 Antibody
PhosphoSolutions
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DETAILS
- Form: Antigen Affinity Purified
- Gene: PRG3
- Host: Rabbit
- Type: Primary Antibody
- Buffer: PBS + 0.02% NaN3
- Target: PRG3
- Isotype: IgG
- Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
- Shipping: Blue Ice
- Synonyms: Proteoglycan 3, Eosinophil major basic protein homolog, Prepro-major basic protein homolog, Prepro-MBPH
- Clonality: Rabbit Polyclonal
- Expiration: After date of receipt, stable for at least 1 year at -20°C.
- Specificity: Reacts with the 41 kDa human PRG3 protein. This sequence is 87% identical in mouse.
- Applications: WB
- Physical State: Liquid
- Quality Control: Western blots performed on each lot.
- Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
- Dilution Range Wb: 1:500-1:1000
- Immunogen Species: Human
- Species Reactivity: Human
- Target Description: The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway
- Uniprot Number Immunogen Species: Q9Y2Y8