ATP1B2 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 482
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: ATP1B2
Other Names: Sodium/potassium-transporting ATPase subunit beta-2, Adhesion molecule in glia, AMOG, Sodium/potassium-dependent ATPase subunit beta-2, ATP1B2
Availability: 2 weeks
Bio Background: The protein belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Bio References: Guey,L.T., et.al, Eur. Urol. 57 (2), 283-292 (2010)Tokhtaeva,E., et.al, Biochemistry 48 (48), 11421-11431 (2009)Hosgood,H.D. et.al, Respir Med 103 (12), 1866-1870 (2009)
Primary Accession: P14415
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP9271c was selected from the Center region of human ATP1B2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.