DESCRIPTION

• Aa: 19-239
• Mw: 54 kDa
• Tags: C-terminal Fc fusion (Human IgG1), C-terminal Avi-tag™
• Format: Aqueous buffer solution
• Genbank: NM_014143
• Species: Human
• Uniprot: Q9NZQ7
• Shiptemp: -80°C (dry ice)
• Synonyms: Programmed Cell Death 1 Ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, CD274, PDCD1L1
• Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
• Category: Immunotherapy/Protein
• References: 1. Freeman, G.J., et al. J. Exp. Med. 2000; 192(7): 1027-1034 2. Dong, H., et al., Nat. Med. 1999; 5(12): 1365-1369.
• Description: Human secreted Programmed Cell Death 1 Ligand 1 (PD-L1)-Fc fusion protein, also known as CD274 and B7 homolog 1 (B7-H1) with a R113A mutation, GenBank Accession No. NM_014143, amino acids 19-239, fused at the Cterminus with the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag™ technology. MW = 54 kDa.
• Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for the study of protein-protein interaction, epitope mapping, and in vitro and in vivo protein function.
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 71105-2, 71213, 72016, 79572, 79512
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Immunotherapy