SPP1 Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 6696
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: SPP1
Other Names: Osteopontin, Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, SPP-1, Urinary stone protein, Uropontin, SPP1, BNSP, OPN
Availability: 2 weeks
Bio Background: SPP1 binds tightly to hydroxyapatite. The protein appears to form an integral part of the mineralized matrix and probably important to cell-matrix interaction. It acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
Bio References: Macri,A., Tumori 95 (1), 48-52 (2009)Agnihotri,R., J. Biol. Chem. 276 (30), 28261-28267 (2001)
Primary Accession: P10451
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6555a was selected from the N-term region of human SPP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.