Anti-eIF1A Antibody [JE64-52]

DESCRIPTION

Eukaryotic translation initiation factor 1A, X-chromosomal (eIF1A) is a protein that in humans is encoded by the EIF1AX gene. This gene encodes an essential eukaryotic translation initiation factor. The protein is a component of the 43S pre-initiation complex (PIC), which mediates the recruitment of the small 40S ribosomal subunit to the 5' cap of messenger RNAs. eIF1A is a small protein (17 kDa in budding yeast) and a component of the 43S preinitiation complexes (PIC). eIF1A binds near the ribosomal A-site, in a manner similar to the functionally related bacterial counterpart IF1. Mutations in this gene have been recurrently seen associated to cases of uveal melanoma with disomy 3. eIF1A is mutated in thyroid cancers. EIF1AX has been shown to interact with IPO13.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: P47813 Human
Clone Id: JE64-52
Clonality: Recombinant Rabbit monoclonal Antibody
Conjugate: Non-conjugated
Alias Names: eIF-1A antibody eIF-1A X isoform antibody eIF-4C antibody EIF1A antibody EIF1AP1 antibody EIF1AX antibody EIF4C antibody eukaryotic translation initiation factor 1A X-linked antibody eukaryotic translation initiation factor 1A, X chromosome antibody Eukaryotic translation initiation factor 1A, X-chromosomal antibody eukaryotic translation initiation factor 4C antibody Putative eukaryotic translation initiation factor 1A antibody
Application: WB
Epitope Region: Synthetic peptide within human eIF1A aa 71-120/144.
Protein Target: EIF1AX
Target Species: Human
Species Reactivity: Human