2104759-25mg 2104759-5mg
HA-100 Dihydrochloride
Biogems
DETAILS
- Purity: ≥95%
- Synonyms: AGN-PC-00L2ST, SCHEMBL5176161, 1-(5-ISOQUINOLINESULFONYL)-PIPERAZINE
- Cas Number: 210297-47-5
- References: Kim, J. H., Do, H. J., Wang, W. H., Macháty, Z., Han, Y. M., Day, B. N., & Prather, R. S. (1999). A protein tyrosine phosphatase inhibitor, sodium orthovanadate, causes parthenogenetic activation of pig oocytes via an increase in protein tyrosine kinase activity. Biology of reproduction, 61(4), 900-905. Chen, G., Gulbranson, D. R., Hou, Z., Bolin, J. M., Ruotti, V., Probasco, M. D., ... & Thomson, J. A. (2011). Chemically defined conditions for human iPSC derivation and culture. Nature methods, 8(5), 424-429. Howden, S. E., Gore, A., Li, Z., Fung, H. L., Nisler, B. S., Nie, J., ... & Thomson, J. A. (2011). Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. Proceedings of the National Academy of Sciences, 108(16), 6537-6542.
- Application: FA
- Formulation: Crystalline solid
- Chemical Name: 5-piperazin-1-ylsulfonylisoquinoline;dihydrochloride dihydrochloride
- Molecular Weight: 350.3
- Molecular Formula: C13H15N3O2S 2HCl
- Storage Conditions: Product should be kept at -20°C.
- Pubchem Openeye Can Smiles: C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl
DESCRIPTION
HA-100 is a protein kinase inhibitor, effecting PKA, PKC, and PKG. It is reported to aid in the survivability of pluripotent stem cells and useful in increasing the efficiency of the chemical reprogramming of human fibroblasts.
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