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Recombinant Rat IL-3beta



IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Rat IL-3beta is a 16.3 kDa globular protein containing 144 amino acid residues.


  • Gene Id: 24495
  • Uniprot: P97688
  • Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of thymidine uptake by murine MC-9 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥1.0 x 10^5 units/mg.
  • Category: RUO Cytokines
  • Subcategory: Growth Factors & Cytokines
  • Research Areas: AIDS/HIV, Cancer, Cell Culture, Diabetes/Weight Regulation, Immune System, Stem Cells and Differentiation
  • Alternative Names: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
  • Species of Origin: Rat
  • Expression System Source: E.coli