mouse monoclonal IgM; IGFBPL1 Antibody (C-5) is an IgM κ mouse monoclonal IGFBPL1 antibody (also designated IGFBPRP4 antibody, or IGFBP-related protein 10 antibody) that detects the IGFBPL1 protein of mouse, rat and human origin by WB, IP, IF and ELISA. IGFBPL1 Antibody (C-5) is available as the non-conjugated anti-IGFBPL1 antibody. IGFBPL1 (Insulin-like growth factor-binding protein-like 1) is a secreted IGF (Insulin-like growth factor) binding protein that is known to contain an Ig-like C2-type (immunoglobulin-like) domain, an IGFBP N-terminal domain and a Kazal-like domain. IGF-binding proteins characteristically act to extend the half-life of IGFs and may influence the growth promoting effects of the IGFs. The interaction of IGFBPs with IGFs can affect cell surface receptors, specifically, IGFBPs may enhance or decrease a cells insulin sensitivity. IGFBPL1 has been found to be down-regulated in multiple tumors and thus may be a likely tumor suppressor candidate. Highly expressed in both brain and testis, IGFBPL1 is found at lower levels in the prostate, bladder and lung.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.