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HY-112724

Scientist.com Supplier

Ivarmacitinib

MedChem Express

- Open Babel Depiction N N N H N N H 3 C H 3 C N O HN S N O

DESCRIPTION

Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects[1][2].

DETAILS

  • Purity: >98%
  • Smiles: O=C(N1C[C@@]2([H])[C@@](C[C@H](N(C)C3=C4C(NC=C4)=NC=N3)C2)([H])C1)NC5=NC(OC)=NS5
  • Category: Reference compound
  • Lead Time: 1-2 days
  • Cas Number: 1445987-21-2
  • Molecular Weight: 414.48
  • Molecular Formula: C18H22N8O2S

Lead Time: 1 - 2 weeks

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