p300 (KAT3B), His-GST-tag Recombinant

DESCRIPTION

Human E1A binding protein p300, also known as EP300, KAT3B, or RSTS2, GenBank Accession No. NM_001429, a.a. 965-1810, with N-terminal His-GST-tag, MW=125 kDa, expressed in Sf9 cells via a baculovirus expression system.

DETAILS

Aa: 965-1810
Mw: 125 kDa
Tags: N-terminal His-GST-tags
Format: Aqueous buffer solution
Genbank: NM_001429
Species: Human
Uniprot: Q09472
Shiptemp: -80°C (dry ice)
Synonyms: EP300, KAT3B, RSTS2, E1A binding protein
Warnings: Avoid freeze/thaw cycles.
Category: Acetyltransferase/Enzymes
References: 1. Gui, Y., et al., Nat. Genet. 2011 Aug 7; 43(9) : 875 - 878.2. Morin, R.D., et al., Nature. 2011 Jul 27; 476(7360) : 298 - 303. 3. Zhao, Z., et al., Brain Res. Bull. 2011 Oct 10; 86(3-4) : 189 - 194. Product Specific Reference(s): 1. Furdas, S.D. et al., Med. Chem. Commun. 2014; 5: 1856-1862.2. Liao, D., et al., Cancer. Epigenetics. 2005; 1238: 539-548.
Description: Human E1A binding protein p300, also known as EP300, KAT3B, or RSTS2, GenBank Accession No. NM_001429, a.a. 965-1810, with N-terminal His-GST-tag, MW=125 kDa, expressed in Sf9 cells via a baculovirus expression system.
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, and 20% glycerol.
Unspsc Code: 12352202
Unspsc Name: Proteins
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Host Species: insect
Product Type: Protein
Host Cell Line: Sf9 cells
Biosafety Level: Not applicable (BSL-1)
Assay Conditions: Assayed with the BPS Bioscience Fluorogenic p300 Assay Kit, Cat. # 50092, per manufacturer's instructions.
Related Products: 50072, 50074, 79705, 79772
Specific Activity: ≥357 pmole/min/µg
Storage Stability: At least 6 months at -80°C.
Scientific Category: Acetyltransferase