NCK1 Antibody (N-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 4690
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: NCK1
Other Names: Cytoplasmic protein NCK1, NCK adaptor protein 1, Nck-1, SH2/SH3 adaptor protein NCK-alpha, NCK1, NCK
Availability: 2 weeks
Bio Background: The protein encoded by this gene is one of the signalingand transforming proteins containing Src homology 2 and 3 (SH2 andSH3) domains. It is located in the cytoplasm and is an adaptorprotein involved in transducing signals from receptor tyrosinekinases to downstream signal recipients such as RAS. Alternativelyspliced transcript variants encoding different isoforms have beenfound.
Bio References: Barda-Saad, M., et al. EMBO J. 29(14):2315-2328(2010)Gehmlich, K., et al. Eur. J. Cell Biol. 89(5):351-364(2010)Preisinger, C., et al. Cell. Signal. 22(5):848-856(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Voss, M., et al. BMC Immunol. 10, 53 (2009) :
Primary Accession: P16333
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP13726a was selected from the N-term region of NCK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.