T14338
Atabecestat
TargetMol
DESCRIPTION
Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF Aβ reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment[1].
DETAILS
- Cas: 1200493-78-2
- Purity: 99.77%
- Smiles: C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
- Category: Compound
- Molecular Weight: 367.4
- Molecular Formula: C18H14FN5OS
Lead Time: < 1 week
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