KU-0060648

DESCRIPTION

KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.

DETAILS

Cas: 881375-00-4
Purity: 99.21%
Smiles: N(C(CN1CCN(CC)CC1)=O)C2=C3C(=C(C=C2)C4=C5C(C(=O)C=C(O5)N6CCOCC6)=CC=C4)SC=7C3=CC=CC7
Category: Compound
Molecular Weight: 582.71
Molecular Formula: C33H34N4O4S

Lead Time: 4 - 5 weeks