Anti-Myosin 13/Extraocular Myosin (Hinge region) Antibody

DETAILS

Form: Antigen Affinity Purified
Gene: MYH13
Host: Rabbit
Rrid: AB_2713977
Type: Primary Antibody
Buffer: PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Target: Myosin 13/Extraocular Myosin (Hinge region)
Isotype: IgG
Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Shipping: Blue Ice
Synonyms: Myh13, myosin heavy chain
Clonality: Rabbit Polyclonal
Immunogen: A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the hinge region from mouse MYH13/extraocular myosin. This sequence has 100% identity with rat and human MYH13, and has low homology to other myosin family members.
Expiration: After date of receipt, stable for at least 1 year at -20°C.
Specificity: The antibody detects a 215 kDa* protein corresponding to the apparent molecular mass of MYH13 on SDS-PAGE immunoblots of mouse extraocular muscle, and does not detect MYHs in mouse diaphragm, gastrocnemius, or brain.
Applications: WB, IHC
Conjugate Exem: Unconjugated
Physical State: Liquid
Quality Control: Western blots performed on each lot.
Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Molecular Weight: 215
Dilution Range Wb: 1:1000
Immunogen Species: Mouse
Dilution Range Ihc: 1:150
Species Reactivity: Human, Mouse, and Rat
Target Description: Myosin is a highly conserved, ubiquitous protein found in all eukaryotic cells, where it provides the motor function for diverse movements such as cytokinesis, phagocytosis, and muscle contraction. All myosins contain an amino-terminal motor/head domain and a carboxy-terminal tail domain. The class II myosins, consist of the conventional two-headed myosins that form filaments and are composed of two myosin heavy chain (MYH) subunits and four myosin light chain subunits. There are 15 MYH genes identified as Class II myosins and these include six skeletal muscle MYHs (MYH1, MYH2, MYH3, MYH4, MYH8, MYH13), three cardiac MYHs (MYH6, MYH7, MYH7B) and two non-muscle MYHs (MYH9, MYH10), as well as a smooth muscle MYH (MYH11).
Uniprot Number Immunogen Species: B1AR69