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Human Bone Morphogenetic Protein 2, BMP-2 ELISA Kit

Bioassay Technology Laboratory


Induces cartilage and bone formation (PubMed: 3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed: 24362451).


  • GeneID: 650
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 44,702
  • Synonyms: BMP 2;BMP2;BMP-2;BMP-2A;Bone morphogenetic protein 2;Bone morphogenetic protein 2A
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: BMP2
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.01ng/ml
  • Target Protein: BMP2
  • Detection Range: 0.05-15ng/ml
  • Full Product Name: Bone Morphogenetic Protein 2
  • Standard Solution: 16ng/ml
  • UniProt Accession: P12643