Human Bone Morphogenetic Protein 2, BMP-2 ELISA Kit

DESCRIPTION

Induces cartilage and bone formation (PubMed: 3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed: 24362451).

DETAILS

GeneID: 650
Species: Human
Storage: 2-8ºC
MASS(Da): 44,702
Synonyms: BMP 2;BMP2;BMP-2;BMP-2A;Bone morphogenetic protein 2;Bone morphogenetic protein 2A
Assay Time: 1h 30m
Assay Type: Sandwich
Gene Names: BMP2
Reactivity: Human
Sample Type: Serum, plasma, cell culture supernates
Sensitivity: 0.01ng/ml
Target Protein: BMP2
Detection Range: 0.05-15ng/ml
Full Product Name: Bone Morphogenetic Protein 2
Standard Solution: 16ng/ml
UniProt Accession: P12643